IPOX® Health Innovation Index (IPHI)
The IPOX® Health Innovation Index (IPHI) is a diverse and dynamic portfolio consisting of leading companies in the healthcare and biotechnology sectors, focusing on recent listings (e.g. IPOs, Spin-Offs and SPACs) as well as acquirers of biotech innovation (“IPO M&As”). Using this strategy, the index captures the performance of both established and emerging players focused on innovative solutions, novel therapies, and cutting-edge medical technologies.
Health Innovation Megatrends tracked by the Index
Weight-Loss Treatments (GLP-1)
Select companies at the forefront of weight-loss treatments, particularly those focused on GLP-1 receptor agonists are actively tracked by the index. These drugs mimic the hormone GLP-1, regulating appetite and blood sugar levels, offering a promising approach to tackling the global obesity epidemic. Key players tracked include firms such as market leader Novo Nordisk, Schott Pharma (a vial manufacturer), and newcomers such as Keros Therapeutics.
GLP-1 therapies represent a major breakthrough in weight management, providing hope for millions struggling with obesity.
Medical Advances for an Aging Population
As the global population ages, there is a growing need for treatments targeting age-related diseases. The index tracks companies focused on age-related macular degeneration (AMD) and other eye diseases, such as Glaukos and Apellis Pharmaceuticals, which are developing treatments to preserve and restore vision in older adults. The index also includes Eli Lilly, a leader in Alzheimer's research. These companies are working on groundbreaking treatments to improve the quality of life for the elderly and reduce the societal costs of an aging population.
Cutting-Edge Cancer Therapies
The index tracks companies pioneering cutting-edge cancer treatments, including CAR T-cell therapy. This revolutionary approach involves genetically modifying a patient's immune cells to target and destroy cancer cells. Caribou Biosciences and Arcellx Inc are just two key players in this field tracked by the index. CAR T represents a major advance in personalized cancer treatment, offering hope for patients with certain blood cancers who have exhausted other treatment options.
Groundbreaking Medical Devices and New Treatments
The index also tracks companies developing innovative medical devices and treatments across various specialties. TransMedics is revolutionizing organ transplantation with technologies for preserving and assessing donor organs. Procept BioRobotics is advancing minimally invasive prostate surgery with its robotic platform. Shockwave Medical is development treatments for calcified plaque in blood vessels to prevent serious cardiovascular events, recently garnering attention as an M&A target as large firms seek out recent IPOs to inject innovation.
By licensing the IPOX® Health Innovation Index, investors can gain exposure to these groundbreaking advancements in the healthcare and biotechnology sectors, potentially benefiting from the growth and success of the innovative companies tracked by the index.
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